Dental caries remain a public health problem for many developing countries and for underprivileged populations in developed countries. This paper outlines the historical development of public health approaches to the use of fluoride and comments on their effectiveness. Early research and development was concerned with waterborne fluorides. both naturally occurring and added. https://www.bekindtopets.com/save-now-Nobivac-Canine-1-DAPPv-Cv-limited-choice/